Mapenem Dosage & Drug Information

Concise Prescribing Info

Contents

Meropenem trihydrate

Indications/Uses

Lower resp tract infections, nosocomial pneumonias, UTI, gynecological & skin infections; peritonitis, meningitis, septicemia, presumed infections in neutropenic patients.

Dosage/Direction for Use

Adult 500 mg-1 g IV 8 hrly. Meningitis 2 g 8 hrly. Childn >3 mth-12 yr 10-20 mg/kg 8 hrly. Meningitis 40 mg/kg 8 hrly. Infection in neutropenic patients 20 mg/kg 8 hrly.

Contraindications

Hypersensitivity to carbapenem, penicillins & other β-lactams.

Special Precautions

Monitor organ system function including hepatic, renal & hematopoietic; seizures, pseudomembraneous colitis.

Adverse Reactions

Inflammation, thrombophlebitis & pain at inj site. Headache, paresthesia, convulsion, rash, pruritus, urticaria, abdominal pain, nausea, vomiting, diarrhea, leucopenia, neutropenia.

View ADR Reporting Link

Drug Interactions

Probenecid increases elimination t_½.

MIMS Class

Other Beta-Lactams

ATC Classification

J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.

Thai FDA Category

Presentation/Packing

Form

Mapenem powd for inj 1 g

Packing/Price

1's

Form

Mapenem powd for inj 500 mg

Packing/Price

1's

Mapenem

meropenem

Manufacturer:

Siam Bheasach

Distributor:

Siam Pharmaceutical