Dermacaine: Side Effects & Dosing

Indications/Uses

Topical anesth of skin, genital mucosa & leg ulcers.

Dosage/Direction for Use

Skin Adult Apply a thick layer approx 1.5-2 g/10 cm² covered w/ occlusive dressing 1-2 hr before start of surgery. Childn Approx 1 g/10 cm² covered w/ occlusive dressing. Childn 6-12 yr Up to 20 g & 200 cm², 1-5 yr Up to 10 g & 100 cm². Infant 3-11 mth Up to 2 g & 20 cm². Neonates 0-2 mth Up to 1 g & 10 cm². Genital mucosa Adult Approx 5-10 g for 5-10 min. No occlusive dressing is required. Commence procedure immediately thereafter. Leg ulcer Apply a thick layer approx 1-2 g/10 cm² up to a total of 10 g. Cover w/ an occlusive dressing for at least 30 min. Up to 60 min may improve the anesth further. Start cleansing w/o delay after cream removal.

Contraindications

Hypersensitivity to amide-type local anesth.

Special Precautions

Do not apply to open wounds, genital mucosa of childn, impaired tympanic membrane. Atopic dermatitis. Avoid contact w/ eyes. Monitor methaemoglobin levels on childn, infants 0-12 mth & neonates. Not to be used in intracutaneous inj of a live vaccine eg, BCG.

Adverse Reactions

Local reactions eg, paleness, erythema (redness) & oedema. Mild burning or itching sensation at application site.

View ADR Reporting Link

Drug Interactions

Increased risk in the methaemoglobin level w/ sulphonamides.

MIMS Class

Anaesthetics - Local & General

ATC Classification

N01BB20 - combinations ; Belongs to the class of amides. Used as local anesthetics.

Thai FDA Category

E-D

Presentation/Packing

Form

Dermacaine cream

Packing/Price

30 g x 1's

Dermacaine

lidocaine + prilocaine

Manufacturer:

SR Pharma

Distributor:

SR Pharma