Cerezyme: Side Effects & Dosing

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing

Concise Prescribing Info

Contents

Imiglucerase

Indications/Uses

Long-term enzyme replacement therapy for ped & adult w/ a confirmed diagnosis of non-neuronopathic (type 1) or chronic neuronopathic (type 3) Gaucher disease & exhibit anemia, thrombocytopenia, bone disease, hepatomegaly or splenomegaly.

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Dosage/Direction for Use

Individualised dosage. Initially 2.5 U/kg body wt 3 times a wk to 60 U/kg once every 2 wk by IV infusion over 1-2 hr.

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Overdosage

View Cerezyme overdosage for action to be taken in the event of an overdose.

Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Cerezyme detailed prescribing information

Special Precautions

Resp symptoms in the absence of fever, pulmonary HTN; previous Ceredase therapy. Pregnancy & lactation. Childn <2 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Pruritus, inj site reactions, flushing, urticaria, angioedema, chest discomfort, dyspnea, coughing, cyanosis, hypotension, nausea, abdominal pain, vomiting, diarrhea, rash, fatigue, headache, fever, dizziness, chills, back ache & tachycardia.

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Storage

View Cerezyme storage conditions for details to ensure optimal shelf-life.

Description

View Cerezyme description for details of the chemical structure and excipients (inactive components).

Action

View Cerezyme mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Other Agents Affecting Metabolism

ATC Classification

A16AB02 - imiglucerase ; Belongs to the class of enzymes. Used in the treatment of alimentary tract and metabolism problems.

Thai FDA Category

Presentation/Packing

Form

Cerezyme inj 400 U

Packing/Price

1's

Cerezyme

imiglucerase

Manufacturer:

Sanofi-Aventis

Distributor:

DKSH