Cefazol: Side Effects & Dosing

Indications/Uses

Resp tract, skin, soft tissue, post-op, GIT, GUT infections. Bacteraemia, septicaemia, endocarditis, osteomyelitis.

Dosage/Direction for Use

IV infusion or slow IV Mild to moderate bacterial infections 1.5-2 g/day in 2-3 divided doses. Severe bacterial infections 3-4 g/day in 2-3 divided doses.

Contraindications

Hypersensitivity.

Special Precautions

Penicillin-allergic patients. Impaired renal function. Patients receiving potent diuretics & nephrotoxic antibiotics.

Adverse Reactions

Diarrhea, hypersensitivity, eosinophilia, genital & oral candidiasis, phlebitis. Rarely, pseudomembranous colitis, anaphylaxis, neutropenia, thrombocytopenia, leucopenia.

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Drug Interactions

Bacteriostatic antibiotics may reduce cephalosporin effectiveness. Probenecid may increase & prolong cephalosporin plasma levels & toxicity.

MIMS Class

Cephalosporins

ATC Classification

J01DB04 - cefazolin ; Belongs to the class of first-generation cephalosporins. Used in the systemic treatment of infections.

Thai FDA Category

S

Presentation/Packing

Form

Cefazol infusion 1 g

Packing/Price

50 × 1's

Cefazol

cefazolin

Manufacturer:

General Drugs House

Distributor:

General Drugs House