Brexin: Side Effects & Dosing

Indications/Uses

Arthritis & related disorders (RA, OA), acute musculoskeletal disorders (tendinitis, bursitis, post-traumatic pain); post-op pain. Symptomatic treatment of primary dysmenorrhea.

Dosage/Direction for Use

20 mg/day. Elderly 10 mg/day.

Administration

Should be taken with food: Take immediately after meals.

Contraindications

Hypersensitivity to NSAIDs or aspirin. GI ulcer, gastritis, dyspepsia. Severe hepatic or renal disease. Severe heart failure, severe HTN, severe blood alterations or hemorrhagic diathesis. Pregnancy & lactation. Childn.

Special Precautions

Upper GIT disorders, CV insufficiency, HTN, hepatic or renal impairment, renal hypoperfusion, blood diseases, asthma, diabetes. Elderly. Prolonged use. Concomitant diuretics. Avoid alcohol.

Adverse Reactions

Most common: GI disturbances (nausea, epigastric distress, constipation & diarrhea). Others: Hypersensitivity, headache, vertigo, asthenia, changes in blood chemistry, increased BUN.

View ADR Reporting Link

Drug Interactions

Diuretics, lithium, glucocorticoids, quinolones, drugs affecting serum K, anticoagulants. Alcohol.

MIMS Class

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

ATC Classification

M01AC01 - piroxicam ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, oxicams.

Thai FDA Category

D

Presentation/Packing

Form

Brexin tab 20 mg

Packing/Price

20's

Brexin

piroxicam beta-cyclodextrin

Manufacturer:

Chiesi

Distributor:

Pacific Healthcare