News & Updates
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Novel intravaginal device for postpartum bleeding passes muster in phase II trial
A less invasive intravaginal device that facilitates bimanual uterine compression appears to work well in the treatment of postpartum haemorrhage, according to the results of a phase II trial.
Selgantolimod well tolerated, induces serologic changes in CHB
Treatment with the oral Toll-like receptor 8 (TLR8) agonist selgantolimod once weekly for 24 weeks is well tolerated and generally safe in patients with chronic hepatitis B (CHB) under viral suppression, according to a recent study.
Gene links breast cancer to stress, circadian disruption
Two researchers from the Philippines have discovered a gene the connects breast cancer development to stress and body clock disruption. In a recent study, they have shown the mechanism behind hormone and circadian regulation of the tumour-suppressor gene, Krüppel-like factor 9 (KLF9), and its effect on breast cancer progression.
Deep-brain stimulation affords greater seizure reduction than vagus nerve stimulation
Among the neurostimulation devices used in the treatment of generalized epilepsy, deep-brain stimulation performs better than vagus nerve stimulation at reducing seizure frequency, as reported in a study. On the other hand, while results for responsive neurostimulation are promising, further research is needed.
Peg lambda cuts hospitalization, ER visits in COVID-19 outpatients
Early treatment with a single dose of pegylated recombinant IL-29 type III interferon (IFN), otherwise known as peg lambda, significantly reduced clinical events in the phase III TOGETHER study evaluating mostly vaccinated, acutely symptomatic COVID-19 outpatients.
COVID-19 infection in early pregnancy ups risk of stillbirth
Pregnant women who contract COVID-19 during early and mid-pregnancy are at risk of stillbirth, but this risk may not be present when infection occurs at any time during the third trimester or before delivery, as reported in a study.