News & Updates
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Investigational imaging agent holds promise for diagnosing renal cancer
In the pivotal phase III ZIRCON study, PET/CT imaging with 89Zr-DFO-girentuximab, an investigational imaging agent, demonstrated potential in the noninvasive identification of clear-cell renal cell carcinoma (ccRCC) in patients with indeterminate renal masses (IDRM).

Add-on immunotherapy improves PFS in 1L advanced or recurrent endometrial cancer
Adding dostarlimab or pembrolizumab to standard first-line (1L) chemotherapy significantly improves progression-free survival (PFS) in patients with advanced or recurrent endometrial cancer, two phase III trials have shown.

Idecabtagene vicleucel boosts PFS and responses vs standard regimens in triple class–exposed R/R MM
Idecabtagene vicleucel (ide-cel), a B-cell maturation antigen–directed chimeric antigen receptor (CAR) T-cell therapy, improves progression-free survival (PFS) and responses vs standard regimens in patients with triple class–exposed relapsed and refractory multiple myeloma (R/R MM), the phase III KarMMa-3 trial has shown.

Endoscopic submucosal dissection safer, more cost-effective than transanal endoscopic microsurgery
In patients with early rectal cancer (ERC), endoscopic submucosal dissection (ESD) appears safer and is associated with shorter hospital stay than transanal endoscopic microsurgery (TEM), results of a recent study have shown.

HF drug provides 24-hour BP-lowering effect in Asians with hypertension
The angiotensin receptor neprilysin inhibitor sacubitril/valsartan, used for heart failure, appears to have potent effects on 24‐hour blood pressure (BP) in Japanese patients with mild‐to‐moderate hypertension and in the subgroup of those with nondipping BP pattern, as shown in a study.

Hysteroscopy not better than vacuum aspiration for managing incomplete miscarriage
The use of hysteroscopy for surgical management of incomplete spontaneous abortion in individuals who intend to conceive again neither leads to more subsequent births nor shows a better safety profile compared with vacuum aspiration, according to the results of the HY-PER trial.



