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High polygenic risk linked to earlier treatment initiation, escalation in glaucoma
High glaucoma polygenic risk score (PRS) shows a significant association with earlier initiation or escalation of intraocular pressure (IOP)-lowering therapy, according to a study, noting the potential usefulness of genetic risk stratification in glaucoma.

Physical activity offsets downsides of abnormal sleep duration
Short and long sleep durations were tied to higher risks for all-cause, cardiovascular disease (CVD), and cancer mortality, but these may be attenuated by engaging in physical activity (PA), a population-based cohort study suggests.

COVID-19 vaccines may elicit cross-reactive T-cell responses for long-term protection
Researchers from the Chinese University of Hong Kong (CUHK) have reported that two doses of either mRNA-based BNT162b2 or inactivated CZ02 vaccine elicit cross-reactive T-cell responses. Identification of vaccine-induced memory T cells indicates potential long-term protection with COVID-19 vaccines.





