News &amp; Updates

Histologic margin status shows a robust association with progression for lentigo maligna melanoma, suggest the results of a recent study.

26 Oct 2023

Is colonic stenting advisable for acute malignant large bowel obstruction?

Insertion of self-expandable metal stents (SEMS) for acute malignant large bowel obstruction (MBO) results in high technical and clinical success with a favourable safety profile, as shown in a recent Singapore study.

Assisted reproductive technology may raise risk of congenital anomalies in infants

Children conceived with assisted reproductive technology (ART) appear to be at slightly increased risk for developing genitourinary abnormalities, according to a study.

Brentuximab vedotin fares well for CTCL in real-world study

Interim findings from a prospective real-world study in Poland demonstrated favourable clinical outcomes and a tolerable safety profile for the CD30-directed antibody-drug conjugate brentuximab vedotin in patients with CD30-expressing cutaneous T-cell lymphoma (CTCL).

One BPG dose may be enough to treat syphilis, regardless of HIV status

Three doses of benzathine penicillin G (BPG) are not necessarily better than a single dose in the treatment of early syphilis in individuals with or without HIV infection, as shown in a study.

26 Oct 2023

mRNA-1647 vaccine well tolerated regardless of CMV serostatus

MRNA-1647, Moderna's investigational mRNA-based vaccine against cytomegalovirus (CMV), is well tolerated in healthy adults regardless of CMV serostatus, according to a study presented at IDWeek 2023.

Monoclonal antibody helps preserve muscle mass regardless of protein intake

25 Oct 2023 by

Treatment with bimagrumab appears to prevent muscle loss resulting from inadequate protein intake and increase muscle mass in the setting of enough protein intake, according to data from phase I and IIa studies.

Vitamin D therapy of no benefit in CKD

For patients with chronic kidney disease (CKD), vitamin D therapy does not appear to lower the risk of death, with uncertain effects on fracture and cardiovascular and kidney outcomes, according to the results of a meta-analysis.

Niraparib tied to more toxicities than olaparib in ovarian cancer

Use of niraparib appears to contribute to a higher risk of haematological toxicities as compared with olaparib, suggests a study. The most common haematological adverse event is anaemia.

25 Oct 2023

Increased BP common after nonsevere COVID-19

25 Oct 2023 by

Blood pressure (BP) tends to rise following a mild or moderate SARS-CoV-2 infection, indicating a potential hypertensive consequence, reveals a study.