News & Updates

Underweight, central obesity, and grade 3 obesity are all associated with a higher risk of death in adults, reveals a study. On the other hand, peripheral fat has an inverse association with mortality.

For pregnant women with type 1 diabetes (T1D), continued use of hybrid-closed loop (HCL) insulin through the postpartum period appears to be safe and efficacious, helping maintain blood sugar control for a significant portion of the time without an increase in hypoglycaemia.

New drug applications approved by US FDA as of 16-31 January 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

The addition of low-dose methotrexate (MTX) to methimazole (MMI) shows a higher rate of discontinuation than MMI alone, as well as significant reductions in thyrotropin-related antibodies (TRAb) levels, in patients with Graves’ disease (GD), reveals a study.

Underweight or obesity during adolescence may contribute to unexplained infertility later in life, as suggested in a large study involving Japanese women.

For patients with type 2 diabetes (T2D) and chronic kidney disease (CKD), continued use of metformin for at least 6 months when eGFR falls below 30 mL/min/1.73m2 appears to yield a small but significant decrease in all-cause mortality, according to a nationwide observational cohort study.

In people with obesity but without diabetes, starting semaglutide treatment appears to be influenced by sociodemographic, health care, and clinical factors, according to a retrospective observational cohort study.

Long-term kidney outcomes in type 2 diabetes (T2D) are similar between empagliflozin- and dapagliflozin-treated patients, aligning with current clinical practice guidelines that do not favour one SGLT2 inhibitor over the other, according to a study.

The use of glucagon-like peptide-1 receptor agonists (GLP-1 RA) significantly lowers blood pressure (BP) in obese or overweight patients, according to a study. This beneficial effect persists across diabetic status, duration of treatment, and route of administration.