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LBB performs better than standard BiV pacing for CRT in chronic heart failure
For chronic heart failure patients requiring cardiac resynchronization therapy (CRT), the use of left bundle branch (LBB) pacing yields superior clinical outcomes compared with the traditional biventricular (BiV) pacing, as shown in the results of the HeartSync-LBBP trial.

Does CKD reduce tirzepatide benefits on HFpEF patients with obesity?
Long-term treatment with tirzepatide results in improved renal function in patients with heart failure with preserved ejection fraction (HFpEF) and obesity, regardless of the absence or presence of chronic kidney disease (CKD), according to a post hoc analysis of the SUMMIT trial presented at ACC.25.

Stepwise DAPT de-escalation on par with standard therapy in ACS
A stepwise dual antiplatelet therapy (DAPT) de-escalation strategy among patients with acute coronary syndrome (ACS) who could be treated by paclitaxel-coated balloons without stents demonstrates noninferiority to the standard 12-month DAPT for all net adverse clinical events, according to a study.





