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Diet-induced weight loss tied to altered brain connectivity
Individuals with obesity who underwent a short-term, low-calorie diet demonstrate a multifaceted body response, including an increased brain connectivity in the limbic‒temporal network (emotion and memory) as well as hormone and eating behaviour changes that seem relevant for recovering the weight lost, a recent study has shown.

PCC does not improve outcomes for Chinese patients with DOAC-associated ICH
Prothrombin complex concentrate (PCC) treatment does not improve functional outcomes or reduce haematoma expansion or mortality in Chinese atrial fibrillation (AF) patients with direct-acting oral anticoagulant (DOAC)–associated intracerebral haemorrhage (ICH), researchers from the Chinese University of Hong Kong (CUHK) have reported.

Disrupted circadian rhythm a modifiable risk factor for Alzheimer’s disease?
Circadian rhythm disruption appears to precede the accumulation of amyloid-beta plaques and potentially represents a modifiable risk factor for Alzheimer's disease (AD), according to a study.

Is it safe to use conditionally ordered LMWH in cancer patients with VTE?
Conditional orders of low molecular weight heparin (LMWH) based on platelet values appears safe and effective in the treatment of venous thromboembolism (VTE) in patients with malignant haematology (MH) experiencing thrombocytopenia, a study has shown. In addition, worsening or new VTE has not been reported among study participants.





