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Antidepressant nonresponders may benefit from rTMS
Repetitive transcranial magnetic stimulation (rTMS) demonstrates greater reduction in depressive symptoms than switching of antidepressant medications in patients with moderately treatment-resistant depression, reveals a study.

Ustekinumab biosimilar SB17 boasts similar efficacy, safety in psoriasis
SB17, a proposed ustekinumab (UST) biosimilar, demonstrates comparable efficacy, safety, and pharmacokinetics (PK) to the reference drug, as well as lower immunogenicity up to week 28, among individuals suffering from moderate-to-severe psoriasis, according to a study.

Vitamin D deficiency tied to higher T2D risk
Increased serum concentration of 25(OH)D appears to contribute to a reduced risk of type 2 diabetes (T2D) across the glycaemic spectrum below the threshold for diabetes, reports a study. Improving the lipid profile may be partly responsible for the favourable association.

Conservative excisional margin for small MIS tied to low recurrence
For small-sized melanoma in situ (MIS; <10 mm) on low-risk body sites, wide local excision (WLE) using a 5-mm margin was associated with a low rate of recurrence, a retrospective case series study has shown.




