News & Updates

Switching to a doravirine-based ARV regimen resolves neuropsychiatric AEs that were ongoing during a prior efavirenz-based regimen in DRIVE-AHEAD, with few events persisting 96 weeks after switching — a finding also seen in DRIVE-FORWARD, as shown in post hoc analyses of the OLEs of the two phase III trials

In patients with established coronary artery disease (CAD), clopidogrel appears to provide superior protection against major adverse cardiovascular or cerebrovascular events (MACCE) without increasing the risk of bleeding when compared with aspirin, according to a meta-analysis.

For patients with supratentorial intracerebral haemorrhage (ICH), minimally invasive surgery is not superior to medical management alone in terms of improving mortality and disability outcomes, according to data from the open-label MIND clinical trial.

Individuals with short-term exposure to ozone (O3) air pollution are at risk of myocardial infarction (MI) and stroke requiring hospitalization, according to a systematic review and meta-analysis.

Many people with drug-resistant epilepsy in Singapore do not consider surgery because of the overestimated risk of the surgical procedure and the perception that seizures are nondisabling, according to a local cross-sectional survey study.

People with epilepsy often experience sleep disturbance, which is linked to other problems such as anxiety and depression and negatively affects quality of life (QoL), according to a study from Germany.

Performing craniotomy for drug-resistant focal epilepsy while a patient is awake appears feasible and does not increase the risk of adverse events, including intraoperative epileptic seizures, according to a retrospective, single-centre cohort study.

Influenza-associated acute necrotizing encephalopathy (ANE) carries increased morbidity and mortality in children, according to a case series.

Undergoing bilateral oophorectomy before menopause appears to contribute to an increased risk of migraine, according to a study.

Individuals with familial hypercholesterolemia (FH) appear to be at increased risk of lacunes and cerebral microbleeds, as reported in a study from Japan.