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A pooled analysis of first-in-human and early feasibility studies demonstrates promising 30-day clinical and echocardiographic outcomes with the novel DurAVR transcatheter heart valve (THV) in patients with small aortic annuli (SAA).
Maintaining a healthy lifestyle or making lifestyle changes in early adulthood helps reduce the risk of developing steatotic liver disease in midlife, even for individuals with genetic predisposition, as shown in a study.
Getting a COVID-19 shot prior to or during pregnancy reduces the risks of severe maternal disease outcomes and preterm birth, and this protection remains consistent across different variant periods, according to a study from Canada.
Treatment with the novel natriuretic peptide receptor-1 (NPR-1) agonist XXB750 demonstrates a neutral effect on 24-h ambulatory systolic blood pressure (SBP) in patients with resistant hypertension, as shown by the results of a phase II trial.
Adherence to inhaler therapy among adult asthma patients in Singapore is intermediate or poor, reports a study, noting the importance of targeted interventions.
Quality of life (QOL) among patients with systemic lupus erythematosus (SLE) improves following CD19 chimeric antigen receptor (CAR) T cell therapy, with also helps lessen the socioeconomic burden associated with active disease, a study has shown.
A systematic review and meta-analysis conducted by researchers in Singapore support ceftazidime-avibactam (CAZ/AVI) as a primary therapeutic alternative for the treatment of OXA-48–producing carbapenem-resistant Enterobacterales (CRE).
Low-levels blood lead concentrations in children are associated with the presence of depressive symptoms in later childhood, according to a study.
The tricyclic antidepressant nortriptyline is only as good as placebo in terms of reducing symptoms of functional dyspepsia in preselected patients, according to the results of a multicentre randomized controlled trial.
Blood pressure (BP) shows a linear association with several cardiovascular (CV) and renal outcomes in patients with type 2 diabetes (T2D), reveals a study.