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Psychological, cachectic comorbidities up death risk, exacerbations in COPD
Individuals with potential chronic obstructive pulmonary disease (COPD) in the psychological and cachectic clusters appear to be at increased risk of mortality over 25 years of follow-up, according to a population-based Norwegian study. In addition, these clusters appear to increase the risk of severe COPD exacerbations.

Ebbs and flows in weight influence CVD risk in T2D patients
In individuals with type 2 diabetes (T2D), greater variability in adiposity indices (BMI and waist circumference [WC]) was tied to increased risk of cardiovascular disease (CVD) outcomes and death – but an intensive weight loss programme mitigated this risk, a study suggests.

Low-dose aspirin prevents common GI cancers in Chinese adults without ASCVD
Low-dose aspirin reduces risks of some common gastrointestinal (GI) cancers, including colorectal cancer (CRC) and gastric cancer (GC), in Chinese without atherosclerotic cardiovascular disease (ASCVD), compared with paracetamol, the first population-wide study from the University of Hong Kong (HKU) has shown.

DOACs, LMWH prevent VTE, but increase bleeding, in major noncardiac surgery
Use of direct oral anticoagulants (DOACs) and low molecular weight heparin (LMWH) appears to reduce venous thromboembolism (VTE) in major noncardiac surgery compared with no active treatment, a study has shown. However, it may also increase major bleeding to a similar extent.




