Adult Initially 75-150 mg daily in divided doses after meals. Administer the night-time dose before bedtime. May be increased to up to 300 mg daily in divided doses, take the largest part at bedtime.
Hospitalised patient May be further increased to up to 600 mg daily in divided doses.
Elderly & frail patient Initially 100 mg daily in a single daily dose or divided into several doses. May be increased to up to 150 mg daily if well tolerated. Max daily dose: 300 mg.