Prezel

Neuropathic pain including diabetic peripheral neuropathy & post-herpetic neuralgia in adults. Adjunctive therapy in adults w/ partial seizures w/ or w/o secondary generalisation. Generalised anxiety disorder (GAD) in adults. Fibromyalgia management.

150-600 mg daily in 2 or 3 divided doses. Neuropathic pain Initially 150 mg daily. May increase to 300 mg daily after an interval of 3-7 days to a max of 600 mg daily after an additional 7-day interval if needed. Epilepsy Initially 150 mg daily. May increase to 300 mg daily after 1 wk to a max of 600 mg after an additional wk. GAD 150-600 mg daily in 2 or 3 divided doses. Initially 150 mg daily, may increase to 300 mg daily after 1 wk. Following an additional wk, may increase to 450 mg daily to a max of 600 mg daily after an additional wk. Fibromyalgia 300-450 mg daily. Initially 75 mg bd, may increase to 150 mg bd w/in 1 wk based on efficacy & tolerability. Renal impairment CrCl ≥60 mL/min Initially 150 mg/day. Dose regimen: bd or tds. Max: 600 mg/day, ≥30-<60 mL/min Initially 75 mg/day. Dose regimen: bd or tds. Max: 300 mg/day, ≥15-<30 mL/min Initially 25-50 mg/day. Dose regimen: once daily or bd. Max: 150 mg/day, <15 mL/min Initially 25 mg/day. Dose regimen: once daily. Max: 75 mg/day. Supplementary dosage following haemodialysis Initially 25 mg/day as single dose. Max: 100 mg/day.

May be taken with or without food.

Hypersensitivity.

Drugs for Neuropathic Pain

N02BF02 - pregabalin ; Belongs to the class of gabapentinoids. Used to relieve pain and other conditions.

POM