Oxitan: Side Effects & Dosing

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Core Prescribing Info

Contents

Oxaliplatin

Indications/Uses

In combination w/ 5-fluorouracil & folinic acid for metastatic colorectal cancer; adjuvant treatment of stage III (Duke's C) colon cancer after complete resection of primary tumour.

Dosage/Direction for Use

IV Adult Metastatic colorectal cancer 85 mg/m² infuse over 2-6 hr repeated every 2 wk until disease progression or unacceptable toxicity. Adjuvant setting 85 mg/m² unfuse over 2-6 hr repeated every 2 wk for 12 cycles (6 mth).

Contraindications

Known history of hypersensitivity. Myelosuppression prior to starting 1st course. Peripheral sensitive neuropathy w/ functional impairment prior to 1st course. Severe renal impairment (CrCl <30 mL/min). Lactation.

MIMS Class

Cytotoxic Chemotherapy

ATC Classification

L01XA03 - oxaliplatin ; Belongs to the class of platinum-containing antineoplastic agents. Used in the treatment of cancer.

Regulatory Classification

POM

Presentation/Packing

Form

Oxitan inj 5 mg/mL

Packing/Price

1's

Oxitan

oxaliplatin

Manufacturer:

Fresenius Kabi Oncology