Cisplatin Pfizer: Side Effects & Dosing

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Core Prescribing Info

Contents

Cisplatin

Indications/Uses

Monotherapy or in combination w/ other chemotherapeutic agents for metastatic non-seminomatous germ cell carcinoma, advanced stage refractory ovarian/bladder carcinoma, refractory squamous cell carcinoma of the head & neck.

Dosage/Direction for Use

IV Adult & childn Monotherapy: 50-100 mg/m² as single infusion every 3-4 wk over 6-8 hr or slow infusion of 15-20 mg/m² daily for 5 days every 3-4 wk. Combination therapy w/ the following cytotoxic agents: Testicular cancer Vinblastine, bleomycin, actinomycin D. Ovarian cancer Cyclophosphamide, doxorubicin, hexamethylmelamine, 5-fluorouracil. Head & neck cancer Bleomycin, MTX.

Contraindications

History of hypersensitivity to cisplatin or platinum-containing compd. Hearing disorders. Bone marrow depression. Generalised infections. Renal impairment. Pregnancy & lactation.

MIMS Class

Cytotoxic Chemotherapy

ATC Classification

L01XA01 - cisplatin ; Belongs to the class of platinum-containing antineoplastic agents. Used in the treatment of cancer.

Regulatory Classification

POM

Presentation/Packing

Form

Cisplatin Pfizer inj 1 mg/mL

Packing/Price

1's

Cisplatin Pfizer

cisplatin

Manufacturer:

Bridgewest Perth Pharma