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Caverject

Caverject

alprostadil

Manufacturer:

Pfizer Manufacturing
Information is sourced from publicly available references. The information is for educational purpose of healthcare professionals and we are not liable for any loss or damage.
Core Prescribing Info
Contents
Alprostadil
Indications/Uses
Erectile dysfunction due to neurogenic, vasculogenic, psychogenic, or mixed etiology. Adjunct to other diagnostic tests in the diagnosis of erectile dysfunction.
Dosage/Direction for Use
Intracavernosal inj Individualized dosage. Initial titration: Titrate dose based on erectile response until dose produce an erection suitable for intercourse not exceeding >60 min. If there is no response, a higher dose may be given after 1 hr but no >2 doses should be given w/in a 24-hr period. If a response occurs, there should be at least 1-day interval before next dose. Maintenance therapy: Recommend inj frequency: No more than once daily & 3 times wkly. Neurogenic etiology (spinal cord injury) Starting dose: 1.25 mcg. 2nd dose: 2.5 mcg. 3rd dose: 5 mcg. Additional increments of 5 mcg until optimal dose is achieved. Vasculogenic, psychogenic or mixed etiology Starting dose: 2.5 mcg. 2nd dose: 5 mcg (partial response), 7.5 mcg (no response). Additional increments of 5-10 mcg until optimal dose is achieved. Adjunct to diagnosis of erectile dysfunction A single dose that induces firm erection is used.
Contraindications
Hypersensitivity. Patients who have conditions that might predispose to priapism (eg, sickle cell anemia or trait, multiple myeloma or leukemia); w/ anatomical deformation of the penis (eg, angulation, cavernosal fibrosis, or Peyronie's disease); penile implants. Men for whom sexual activity is inadvisable or contraindicated. Women. Childn & newborns.
MIMS Class
Drugs for Erectile Dysfunction & Ejaculatory Disorders
ATC Classification
G04BE01 - alprostadil ; Belongs to the class of drugs used in erectile dysfunction.
Presentation/Packing
Form
Caverject powd for soln for inj 20 mcg
Packing/Price
1's
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