Actos: Side Effects & Dosing

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Core Prescribing Info

Contents

Pioglitazone HCl

Indications/Uses

Monotherapy in type 2 DM particularly over wt patients, inadequately controlled by diet & exercise for whom metformin is inappropriate because of contraindications or intolerance; combination w/ metformin or sulphonylurea in patients w/ insufficient glycaemic control.

Dosage/Direction for Use

Adult Monotherapy: Initially 15 or 30 mg once daily. May be increased up to max 45 mg once daily. Combination therapy: The current metformin & sulphonylurea dose can be continued upon initiation of pioglitazone therapy. Max: 45 mg once daily.

Administration

May be taken with or without food.

Contraindications

Hypersensitivity. Cardiac failure or history of cardiac failure (NYHA stages I-IV). Active or history of bladder cancer. Uninvestigated macroscopic haematuria. Combination w/ insulin. Hepatic impairment.

MIMS Class

Antidiabetic Agents

ATC Classification

A10BG03 - pioglitazone ; Belongs to the class of thiazolidinediones. Used in the treatment of diabetes.

Regulatory Classification

POM

Presentation/Packing

Form

Actos tab 15 mg

Packing/Price

1's

Form

Actos tab 30 mg

Packing/Price

1's

Actos

pioglitazone

Manufacturer:

Bora Pharmaceutical