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High-dose iberdomide shows promise in phase II SLE trial

07 Jun 2022 by

In a phase II trial evaluating three doses of the high-affinity cereblon modulator iberdomide, the 0.45-mg dose demonstrated superiority over placebo for individuals with active, moderate-to-severe systemic lupus erythematosus (SLE).

07 Jun 2022

H. pylori eradication suppresses long-term gastric cancer risk

07 Jun 2022 by

Helicobacter pylori eradication treatment leads to large reductions in the risk of gastric cancer and lower rates of associated deaths over 10 years of follow-up, according to a recent meta-analysis.

07 Jun 2022

Secondary immunodeficiency common yet underdiagnosed and undertreated in HK

07 Jun 2022 by

Local data presented at the 26^th HKMF indicates that secondary immunodeficiency (SID), a common disease that can be treated with immunoglobulin (Ig) replacement therapy, is underdiagnosed and undertreated in Hong Kong.

07 Jun 2022

Obesity weakens children’s defense against SARS-CoV-2 infection

07 Jun 2022

In the paediatric population, children with obesity are especially vulnerable to the SARS-CoV-2 virus, a study has found.

07 Jun 2022

Transvaginal sonography accepted by women with PMB if high endometrial Ca detection rate

07 Jun 2022 by

A recent cross-sectional questionnaire study has shown that women with postmenopausal bleeding (PMB) would select transvaginal sonography to measure endometrial thickness (TVS-ET) over gold-standard hysteroscopy with biopsy if TVS-ET achieved a median endometrial cancer detection rate of 95.0 percent.

07 Jun 2022

Erlotinib lowers polyp burden in familial adenomatous polyposis

07 Jun 2022

Treatment with erlotinib is well tolerated and leads to a reduction in duodenal and lower gastrointestinal polyp burden in patients with familial adenomatous polyposis, according to data from a phase II trial.

07 Jun 2022

SPLENDID unmasks benefits of bariatric surgery in cancer

07 Jun 2022 by

New evidence from the SPLENDID study unmasks the benefits of weight loss achieved with bariatric surgery in protecting against cancer.

07 Jun 2022

Molecular stratification useful for fine prognostication of adult gliomas

07 Jun 2022 by

A study conducted by the Chinese University of Hong Kong (CUHK), Fudan University in Shanghai, China, and Zhengzhou University in Zhengzhou, China, has found that a molecular stratification system based on single-gene alterations aids fine prognostication of adult gliomas.

07 Jun 2022