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Catheter-directed thrombolysis trumps systemic anticoagulation for submassive pulmonary embolism
Catheter-directed thrombolysis (CDT) is superior to systemic anticoagulation (SA) for the treatment of submassive pulmonary embolism (sPE), leading to better mortality rates without additional safety signals, a recent meta-analysis has found.

Diabetes status may influence long-term survival in metastatic breast cancer
Long-term overall survival (OS) in patients with metastatic breast cancer (MBC) may be influenced by diabetes status, according to a retrospective study presented at ENDO 2022.

Bariatric surgery cuts obesity-associated cancer, cancer death risks
For individuals with obesity, undergoing weight-loss surgery may be a lifesaver, not only helping avert cancer-related deaths but also preventing the incidence of obesity-associated cancer, according to data from the SPLENDID (Surgical Procedures and Long-term Effectiveness in Neoplastic Disease Incidence and Death) study.

Hypertensive crisis leads to worse outcomes in CKD, ESRD patients
Hypertensive crisis (HTN-C) is a major burden on patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) relative to those without, reveals a study. HTN-C usually results in a higher number of emergency department visits, incidence of hypertensive emergency, hospitalization rate, in-hospital mortality, and cost of care.

Empagliflozin improves outcomes in HFpEF patients regardless of age
Treatment with empagliflozin results in a reduction in heart failure (HF) risk and renal outcomes and in better health-related quality of life (HRQoL) among patients with chronic HF with preserved ejection fraction (HFpEF), a study has shown. In addition, the study drug is well tolerated by older patients.

Cardiovascular events not uncommon in ICU-admitted COVID-19 survivors
One out of five severe COVID-19 survivors who underwent mechanical ventilation have coronary artery disease (CAD), a quarter have subclinical left ventricular dysfunction defined as reduced echocardiographic global longitudinal strain (GLS), and 42 percent have cardiac magnetic resonance (CMR) abnormalities, reports a study.



