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5α-reductase inhibitor treatment implicated in dementia

05 Jan 2023

Men who are receiving treatment with 5α-reductase inhibitors (5-ARIs) are at increased risk of dementia in the immediate period after initiating treatment, a study has shown. Of note, both finasteride and dutasteride are associated with depression, but neither of them is linked to suicide.

05 Jan 2023

Smoking can take a toll on cognitive function

02 Jan 2023 by

Smoking has long been known to be associated with a host of health problems—including lung cancer, heart disease, and chronic obstructive pulmonary disease—and now a recent study names one more: cognitive decline.

02 Jan 2023

Assisted reproductive technology poses no excess risk of multiple sclerosis

01 Jan 2023

Exposure to assisted reproductive technology (ART) does not appear to promote the development of multiple sclerosis, a study has found.

01 Jan 2023

Original New Drug Application Approvals by US FDA (16-31 December 2022)

31 Dec 2022

New drug applications approved by US FDA as of 16 - 31 December 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

31 Dec 2022

Neutrophil-to-lymphocyte ratio predicts ischaemic stroke in Chinese T2DM patients

29 Dec 2022 by

Neutrophil-to-lymphocyte ratio (NLR) is a significant predictor of new-onset ischaemic stroke in Chinese patients with type 2 diabetes mellitus (T2DM), the population-based Hong Kong Diabetes Study has shown.

29 Dec 2022

Sovateltide: A new option to improve neuro outcomes after cerebral ischaemic stroke?

26 Dec 2022 by

The endothelin-B receptor agonist sovateltide appears to improve neurological outcomes in patients with acute cerebral ischaemic stroke (ACIS), according to a phase III trial presented at WSC 2022.

26 Dec 2022

Psychological distress contributes to increased dementia risk

23 Dec 2022

Individuals with symptoms of psychological distress are at increased risk of all-cause dementia, although this association is attenuated by the competing risk of death, according to a study.

23 Dec 2022

HF meds rapid up-titration reduces readmission, mortality after acute HF hospitalization

21 Dec 2022 by

Rapidly maximizing medications in patients discharged from hospital following acute heart failure (AHF) reduced the risk of hospital readmission or death at 180 days, according to results of the STRONG-HF* trial presented at AHA 2022.

21 Dec 2022

Original New Drug Application Approvals by US FDA (1 - 15 December 2022)

19 Dec 2022

New drug applications approved by US FDA as of 01 - 15 December 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

19 Dec 2022

Mindfulness training, exercise of little benefit to patients with subjective cognitive concerns

18 Dec 2022

Interventions that consist of mindfulness training, exercise, or both do not seem to produce any improvements in episodic memory or executive function at 6 months among older adults with subjective cognitive concerns, according to a study.