News &amp; Updates

Individuals with multiple nevi and high genetic predisposition to melanoma appear to have the highest risks of developing second primary melanomas, according to a study.

22 Jan 2023

Monitoring Epstein–Barr viral load may reduce PTLD incidence after liver transplant

Epstein‒Barr virus (EBV) viral load (VL) monitoring can help lower the incidence of post-transplant lymphoproliferative disease (PTLD) following liver transplant in adults, suggests a study.

ADHD medication use carries no excess cardiovascular disease risk

Attention-deficit/hyperactivity disorder (ADHD) medications do not appear to put users at increased risk of cardiovascular disease (CVD), although a modest risk increase for cardiac arrest or tachyarrhythmias cannot be ruled out, according to the results of a meta-analysis.

22 Jan 2023

Mixed heavy metal exposure detrimental to kidney function in postmenopausal women

Mixed heavy metals such as cadmium, lead, and mercury exert adverse effects on kidney function, with the effects more pronounced among postmenopausal than premenopausal women, a study has found.

IV antihypertensives up myocardial injury risk in hospitalized patients with severe hypertension

Use of intravenous (IV) antihypertensive treatment appears to increase the risk of myocardial injury in patients who develop severe hypertension during hospitalization and without acute target end organ damage, reveals a recent study.

21 Jan 2023

Risk of overdose high among young people using benzos for sleep disorders

The use of benzodiazepines to treat common sleep disorders in young people appears to carry a greater risk of drug overdose as compared with alternative pharmacologic treatments, according to a study.

Trastuzumab deruxtecan confers hope as second-line therapy for HER2+ mBC

20 Jan 2023 by

Updated results of the DESTINY-Breast03 trial, presented at SABCS 2022, showed that in patients with HER2+ metastatic breast cancer, second-line treatment with trastuzumab deruxtecan conferred better survival benefits than treatment with trastuzumab emtansine.

20 Jan 2023

Omega-3 supplements lower triglyceride levels in postmenopausal women

Supplementation with omega-3 fatty acids helps reduce triglyceride levels in postmenopausal women, according to a study. This supplement also leads to a modest increase in high- (HDL-C) and low-density lipoprotein cholesterol (LDL-C).

Low baroreflex sensitivity tied to higher BP, BP variability

Lower cardiovagal baroreflex sensitivity (BRS) appears to contribute to a higher mean blood pressure (BP) from the short- to midterm range and to BP variability, albeit not consistently, results of the Maastricht study have shown.

FRSW 107 proven safe, effective in previously treated patients with haemophilia A

20 Jan 2023 by

Use of FRSW 107, a novel homodimer recombinant factor VIII (rFVIII) Fc fusion protein, for prophylaxis and treatment of bleeding episodes is both safe and effective among previously treated adolescent and adult patients with haemophilia A (HA), reports a China study presented at the 64th American Society of Hematology (ASH) Annual Meeting and Exposition.