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Long-term semaglutide reduces diabetes risk
In a prespecified secondary analysis of the SELECT trial, long-term treatment with semaglutide allows more patients with prediabetes to regress to normoglycaemia while reducing progression to diabetes in some patients. However, semaglutide does not slow glycaemic progression over time.

Nearly half of dementia cases preventable by tackling 14 risk factors
Nearly half of dementia cases could be prevented or delayed by addressing 14 modifiable risk factors starting from childhood, including two new risk factors – high LDL-cholesterol (LDL-C) level and untreated vision loss – according to a report of the 2024 Lancet Commission on dementia.

Diet-induced weight loss tied to altered brain connectivity
Individuals with obesity who underwent a short-term, low-calorie diet demonstrate a multifaceted body response, including an increased brain connectivity in the limbic‒temporal network (emotion and memory) as well as hormone and eating behaviour changes that seem relevant for recovering the weight lost, a recent study has shown.





