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Abemaciclib extends survival in early breast cancer
The combination of adjuvant abemaciclib and endocrine therapy (ET) significantly improves overall survival in patients with HR-positive, HER2-negative, node-positive, high-risk early breast cancer compared with ET alone, the phase III monarchE trial has shown.

Paracetamol safe to use during pregnancy: study
The use of paracetamol during pregnancy does not appear to increase the likelihood of autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD), or intellectual disability in children, according to the results of a systematic review and meta-analysis.

COMMIT: Triplet regimen extends PFS in select CRC patients
In the phase III COMMIT* trial, a combination of mFOLFOX6 (FFX), atezolizumab, and bevacizumab significantly improves progression-free survival (PFS) in patients with deficient mismatch repair or microsatellite instability-high metastatic colorectal cancer (dMMR/MSI-H mCRC).

NATALEE updates: Ribociclib benefit in HR+, ERBB– EBC sustained at 4 years
In an updated analysis of the NATALEE* trial, the efficacy benefit of adjuvant ribociclib remains consistent even after the planned 3-year treatment duration for patients with HR+, ERBB2– early breast cancer (EBC).




