News & Updates

Rare and deleterious germline mutations affecting inflammatory response and cellular signaling pathways associate strongly with the time to biochemical recurrence (BCR) after radical treatment in patients with prostate cancer (PrCa), according to a recent study.

In men with lower urinary tract symptoms (LUTS), urinary symptom subdomains show an independent association with modifiable clinical variables such as sleep quality and depression at all time points, a study has found. However, these variables do not predict the degree of improvement in LUTS after assessment and treatment over the medium term.

Heart diseases, chronic obstructive pulmonary disease (COPD), concomitant cancers, and other co-occurring diseases elevate the risk of death in patients with nonmuscular invasive bladder cancer (NMIBC), nonmetastatic muscle invasive bladder cancer (non-MMIBC), and metastatic bladder cancer (MBC), according to a recent study.

In the phase II NEOBLADE* trial, the addition of the multikinase** inhibitor nintedanib to neoadjuvant chemotherapy (CT) consisting of gemcitabine and cisplatin failed to improve pathological complete response (pCR) and progression-free survival (PFS) in individuals with locally advanced muscle-invasive bladder cancer (MIBC).

Men with inflammatory bowel disease (IBD) have a slightly reduced fertility, and this is observed in both ulcerative colitis and Crohn’s disease, as reported in a study.

The use of holmium laser enucleation of the prostate (HoLEP) and robotic-assisted simple prostatectomy (RASP) deliver comparable and good postoperative outcomes in patients with large benign prostatic hyperplasia (BPH), a new study has found.

Frailty is associated with a higher relative risk of 30-day complications, 1-year mortality, and repeat procedures for persistent incontinence or obstructed voiding at 1 year after sling surgery in older adults, suggests a recent study.

Men receiving testosterone therapy (TT) who develop polycythemia are at greater risk for major adverse cardiovascular events (MACE) and venous thromboembolism (VTE) in the first year of therapy, according to a recent study.

Prostate cancer (PCa) patients with higher lymph node (LN) risk scores and Gleason grade who are treated with whole pelvis radiotherapy (WPRT) have better overall survival (OS), reports a study.