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Alcohol-related liver disease poses increased risk of cardiovascular disease
Patients with biopsy-proven alcohol-related liver disease (ALD) appear to have a higher frequency of cardiovascular disease (CVD) than their counterparts without ALD, according to a study. The increased rates are especially pronounced just after ALD diagnosis.

Third-dose vaccine beats tolerance in cirrhotic COVID-19 patients
A third-dose administration of a COVID-19 mRNA vaccine results in a more substantial decrease in COVID-19 in patients with cirrhosis compared with the general population, according to a study. This suggests that the third dose can overcome vaccine hyporesponsiveness in this population.

Slow disease progression seen in people with NAFLD
A 23-year longitudinal follow-up in a population-based cohort has shown a slowly progressive trend in nonalcoholic fatty liver disease (NAFLD), with liver-related outcomes affecting only a small number of people, reports a recent study.

Vebicorvir plus entecavir safe, effective in chronic HBV patients
The addition of vebicorvir to entecavir in treatment-naïve patients with chronic hepatitis B virus (HBV) infection provides further antiviral activity, with a positive safety and tolerability profile, results of a phase II trial have shown.

Freshwater fish-based diet eases liver steatosis in NAFLD patients
Adherence to a freshwater fish-based diet helps regulate the gut microbiota and its metabolites, suggesting benefits in individuals with nonalcoholic fatty liver disease (NAFLD), reveals a study.

Tenofovir alafenamide reduces liver stiffness in CHB patients
Treatment with the nucleos(t)ide analogue (NUC) tenofovir alafenamide (TAF) for 2 years leads to improvements in liver stiffness among patients with chronic hepatitis B (CHB), including those with advanced liver fibrosis, according to a study presented at the IDWeek 2022 in Washington, DC, US.

Hepatitis B vaccine with TLR-9 agonist achieves high protection in people with HIV
Among people living with HIV (PLHIV), immunization with a hepatitis B surface antigen (HBsAg)-based vaccine adjuvanted with a toll-like receptor (TLR)-9 agonist can induce a 100-percent seroprotection rate, according to a study presented at the recently concluded Virtual ID Week 2022.


