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Iron pill safely fills iron stores in CKD patients with anaemia over long term

21 Jun 2021 by

In patients with chronic kidney disease (CKD) and iron-deficiency anaemia, the orally administered ferric maltol appears to yield meaningful and sustained increases in haemoglobin and iron indices, with a low rate of treatment discontinuation due to adverse events, according to the results of the phase III AEGIS-CKD trial and open-label extension.

Iron pill safely fills iron stores in CKD patients with anaemia over long term

21 Jun 2021

Topiramate works for secondary prevention of cyclic vomiting syndrome with red flags

21 Jun 2021

Topiramate appears to be an effective second-line prophylactic medication against moderate-to-severe cyclic vomiting syndrome in adults but at the cost of side effects, a study has shown.

Topiramate works for secondary prevention of cyclic vomiting syndrome with red flags

21 Jun 2021

Pharmacist involvement in paediatric oncology clinic lowers adverse events, readmission

20 Jun 2021

The inclusion of a clinical oncology pharmacist into an ambulatory care pharmacy in paediatric haematology–oncology and transplant clinic results in reduced adverse events and fewer readmission into the hospital, a study has shown.

Pharmacist involvement in paediatric oncology clinic lowers adverse events, readmission

20 Jun 2021

Certain rheuma therapies tied to poorer COVID-19 outcomes, impaired vaccine response

19 Jun 2021 by

Certain therapies used for rheumatic diseases, including rituximab, are associated with worse outcomes for COVID-19 and reduced immune response after COVID-19 vaccination in patients with rheumatic diseases, according to two studies presented at the virtual EULAR 2021 Congress.

Certain rheuma therapies tied to poorer COVID-19 outcomes, impaired vaccine response

19 Jun 2021

Novel method identifies adverse events in cancer drugs early

19 Jun 2021

A unique drug identification protocol can detect adverse events of cancer agents early when applied clinically, according to a study in Japan.

Novel method identifies adverse events in cancer drugs early

19 Jun 2021

Cytarabine in polypropylene syringes stable at 2–8 °C for 28 days

19 Jun 2021

The physical and chemical stability of cytarabine diluted in 0.9% NaCl in polypropylene syringes is at its highest at 2–8 °C, a recent study in Tunisia has found. The 1-mg/mL solution demonstrates better stability at 25 °C relative to those at higher concentrations (5 and 10 mg/mL).

Cytarabine in polypropylene syringes stable at 2–8 °C for 28 days

19 Jun 2021

Secukinumab promising for paediatric enthesitis-related arthritis and juvenile psoriatic arthritis

18 Jun 2021 by

Treatment with the fully human anti-IL17 monoclonal antibody secukinumab resulted in fewer, and a longer time to, disease flares in children and adolescents with enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA), results of the phase III JUNIPERA trial showed.

Secukinumab promising for paediatric enthesitis-related arthritis and juvenile psoriatic arthritis

18 Jun 2021

Rheumatic patients urged to get vaccinated against COVID-19 without treatment interruption

18 Jun 2021 by

Eligible patients with rheumatic diseases (PRDs) are strongly urged to get vaccinated against COVID-19, and the vaccine may be administered while on immunomodulatory therapy, preferably during an inactive disease state, and without requiring testing for postvaccination antibody titres, according to recommendations from the Singapore Chapter of Rheumatologists.

Rheumatic patients urged to get vaccinated against COVID-19 without treatment interruption

18 Jun 2021

Prehospital antibiotics reduce complications in children with pleural effusion/empyema

18 Jun 2021

Prehospital antibiotic therapy (PH-ABT) leads to a marked decrease in the overall rate of bacterial pathogen detection by culture, but not by polymerase chain reaction, in children with parapneumonic pleural effusion (PPE) and pleural empyema (PE), a study has found. PH-ABT also results in a reduced rate of infectious complications but does not have an impact on the overall disease duration.

Prehospital antibiotics reduce complications in children with pleural effusion/empyema

18 Jun 2021

Triple combo works in second-line treatment of multiple myeloma

18 Jun 2021

A treatment combination comprising pomalidomide, bortezomib, and dexamethasone appears to be effective in multiple myeloma patients for whom lenalidomide is no longer an option, including those refractory to lenalidomide, according to the results of the phase III OPTIMISMM trial.

Triple combo works in second-line treatment of multiple myeloma

18 Jun 2021

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Iron pill safely fills iron stores in CKD patients with anaemia over long term

Iron pill safely fills iron stores in CKD patients with anaemia over long term

Topiramate works for secondary prevention of cyclic vomiting syndrome with red flags

Topiramate works for secondary prevention of cyclic vomiting syndrome with red flags

Pharmacist involvement in paediatric oncology clinic lowers adverse events, readmission

Pharmacist involvement in paediatric oncology clinic lowers adverse events, readmission

Certain rheuma therapies tied to poorer COVID-19 outcomes, impaired vaccine response

Certain rheuma therapies tied to poorer COVID-19 outcomes, impaired vaccine response

Novel method identifies adverse events in cancer drugs early

Novel method identifies adverse events in cancer drugs early

Cytarabine in polypropylene syringes stable at 2–8 °C for 28 days

Cytarabine in polypropylene syringes stable at 2–8 °C for 28 days

Secukinumab promising for paediatric enthesitis-related arthritis and juvenile psoriatic arthritis

Secukinumab promising for paediatric enthesitis-related arthritis and juvenile psoriatic arthritis

Rheumatic patients urged to get vaccinated against COVID-19 without treatment interruption

Rheumatic patients urged to get vaccinated against COVID-19 without treatment interruption

Prehospital antibiotics reduce complications in children with pleural effusion/empyema

Prehospital antibiotics reduce complications in children with pleural effusion/empyema

Triple combo works in second-line treatment of multiple myeloma

Triple combo works in second-line treatment of multiple myeloma