News & Updates

A single injection of mRNA-1403, a multivalent norovirus mRNA vaccine, induces a robust serum histo-blood group antigen (HBGA)-blocking antibody response across all dose levels in adults, as shown by interim results of an ongoing phase I/II trial presented at IDWeek 2024. Comparable findings have been observed with serum virus-like particle (VLP)-binding antibody responses.

With the advent of plant-based diets (PBDs), plant-based meat analogues (PBMAs) have emerged as alternative protein sources carrying numerous health benefits. However, a study from Singapore appears to reflect otherwise, showing that PBMAs do not confer cardiometabolic health benefits compared with their animal-based counterparts.

A cohort study conducted by researchers from the University of Hong Kong (HKU) reports a complete response (CR) rate of 46.0 percent among patients with locally advanced, unresectable hepatocellular carcinoma (HCC) who were treated with locoregional therapy (LRT) plus immunotherapy (IO) and a 3-year overall survival (OS) rate of 75.5 percent among patients with CR.

The international, multicentre, randomized phase III GCIG INTERLACE trial reports significantly higher 5-year progression-free survival (PFS) and overall survival (OS) rates with induction chemotherapy followed by chemoradiotherapy (CRT) vs CRT alone in patients with locally advanced cervical cancer.

Wearing a face mask while sleeping shows no adverse effect on cardiopulmonary function in patients with mild-to-moderate obstructive sleep apnoea (OSA), although it can be uncomfortable, particularly when using the N95 mask, according to a study. A surgical mask may be used as an alternative.