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Esaxerenone produces favourable night-time BP-lowering effect in Asians
The novel highly selective mineralocorticoid receptor blocker esaxerenone holds promise in the treatment of nocturnal hypertension, yielding substantial reductions in night-time blood pressure (BP), especially in Japanese patients with a riser pattern, as well as in N-terminal pro B-type natriuretic peptide (NT-proBNP) levels, according to a post hoc analysis of a phase III study.

Peak exercise SBP below predicted value tied to future CVD, mortality
A peak systolic blood pressure (SBP) at clinical exercise testing that is slightly lower than the predicted value appears predictive of future cardiovascular disease (CVD) and mortality, suggests a study. Higher peak SBP, however, is not associated with such risks.

Tranexamic acid ups blood control after CABG, but aggravates perioperative myocardial infarction
While tranexamic acid improves blood control after coronary artery bypass graft (CABG) surgery, it increases the risk of perioperative myocardial infarction, a recent study has found.

Elevated homocysteine level ups mortality risk in hypertensive adults
The interaction of hypertension and total plasma homocysteine (tHcy) levels contributes to the risk of all-cause mortality among middle-aged and older adults, a US study has found. In addition, hypertension may boost the ability of elevated tHcy to aggravate this risk.




