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Patients with rheumatoid arthritis (RA) who have lower bone mineral density (BMD) are more likely to experience endothelial dysfunction but not aortic stiffness, suggests a Singapore study.
Inflammaging plays no significant role in rheumatic immune-related adverse events (Rh-irAEs), as shown by the comparable numbers of overall irAEs and the severity of RH-irAEs between older and younger patients who developed these conditions after treatment with immune checkpoint inhibitors (ICIs), a study has shown.
Patients with systemic sclerosis (SSc) who have diabetic ulcer (DU) are at an increased risk for developing pulmonary arterial hypertension (PAH), reports a study. However, the use of bosentan for preventing DU may reduce such risk.
In patients with knee osteoarthritis (OA), yoga is only as good as strengthening exercises at reducing pain, according to a study.
In children with noninfectious uveitis being treated with adalimumab, tapering speed appears to affect the risk of relapse, with a slow, gradual approach emerging as the optimal strategy, according to a multicentre retrospective cohort study.
Paediatric patients with autoinflammatory diseases undergoing treatment with canakinumab and tocilizumab can be safely vaccinated against hepatitis A, according to a prospective interventional study.
New drug applications approved by US FDA as of 16-31 March 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
New drug applications approved by US FDA as of 1-15 March 2025 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Patients with Sjögren disease (SD) are at heightened risk of mortality from infections, malignancies, and cardiovascular disease (CVD), reveals a study.
Among middle-aged women, low creatinine-cystatin C ratio is predictive of reduced fat-free muscle volumes and poorer gait speeds after more than 6 years, as shown in a study.
