News & Updates

New drug applications approved by US FDA as of 16-31 December 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Noninvasive diagnosis of metabolic dysfunction–associated steatohepatitis (MASH) may become a possibility with a robust blood-based biomarker panel developed by researchers from the Chinese University of Hong Kong (CUHK) and their collaborators in mainland China and the US, which demonstrated high diagnostic accuracy in Asian and American validation cohorts.

The evidence supporting an upfront daratumumab-containing regimen as the SoC for AL amyloidosis is reaffirmed by the significant OS benefit demonstrated in the final analysis of ANDROMEDA

Among patients with primary biliary cholangitis (PBC), treatment with elafibranor improved predicted transplant-free survival rates based on improvements in GLOBE and UK-PBC scores, according to the phase III ELATIVE trial presented at The Liver Meeting 2024.

Treatment with odevixibat led to rapid and sustained improvements in pruritus and serum bile acid (sBA) levels among patients with Alagille syndrome (ALGS), according to the final data of the phase III ASSERT-extension (ASSERT-EXT) study presented at The Liver Meeting 2024.

Among consumers of different types of alcohol, those who consume beer only have the lowest dietary quality compared with those confined to wine or liquor intake or those who consume multiple types of alcohol, according to data presented at TLM 2024.

Statins appear to be beneficial to patients with cirrhosis, being associated with reduced risks of portal hypertension and its complications as well as death, according to a study.

More women are now being included in liver transplant waitlist and undergoing the procedure following the adoption of the updated Model for End-Stage Liver Disease (MELD)—MELD 3.0—with mortality and transplant rates nearly matching those observed in men, according to a retrospective study conducted in the US.