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1HP safe, feasible for tuberculosis prevention in exposed individuals without HIV
Treatment with isoniazid and rifapentine (HP) either for 1 month daily (1HP) or 3 months weekly (3HP) results in high rates of treatment success among people with a positive latent tuberculosis infection test and without HIV infection, a study has shown. The 3HP regimen has slightly lower rates of adverse reactions, but neither exhibits superiority to the other.

ARTISTRY-1 supports switch from complex HIV regimen to a novel single pill
The phase II/III open-label ARTISTRY-1 trial shows that people living with HIV (PWH) may simplify their complex regimen (CR) by switching to a novel daily single-tablet regimen (STR) comprising bictegravir and lenacapavir (BIC+LEN).

Rehab helps resolve platypnoea–orthodeoxia syndrome in COVID-19 patients
Timely and effective rehabilitation interventions can improve orthodeoxia and functional outcome in patients with COVID-19-related platypnoea‒orthodeoxia syndrome (POS), suggests a Singapore study.





