RiteMED Piperacillin + Tazobactam Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Piperacillin Na 4 g, tazobactam Na 500 mg.

Indications/Uses

For documented multi-drug resistant gm -ve infections due to organisms proven or suspected to be susceptible to piperacillin/tazobactam except CNS infections; for polymicrobial infections (eg, mixed aerobic & anaerobic infections).

Click to view RiteMED Piperacillin + Tazobactam detailed prescribing information

Dosage/Direction for Use

IV infusion over 30 min. Adult 3.375 g every 6 hr totalling 13.5 g. Initial presumptive treatment of patients w/ nosocomial pneumonia 16 g piperacillin/2 g tazobactam. Childn >40 kg 4.5 g every 6 hr (16 g piperacillin/2 g tazobactam). CAP, intra-abdominal infections (appendicitis &/or peritonitis, uncomplicated & complicated skin & skin structure infections, pelvic inflammatory disease 3.375 g every 6 hr (16.0 gm Piperacillin/2.0 gm Tazobactam per day) + aminoglycoside. ≥9 mth weighing up to 40 kg CAP, intra-abdominal infections (appendicitis &/or peritonitis, uncomplicated & complicated skin & skin structure infections, pelvic inflammatory disease 100 mg piperacillin + 12.5 mg tazobactam/kg every 8 hr (3.375 g every 6 hr). 2-9 mth CAP, intra-abdominal infections (appendicitis &/or peritonitis, uncomplicated & complicated skin & skin structure infections, pelvic inflammatory disease 80 mg piperacillin/10 mg tazobactam/kg every 8 hr. Usual duration of therapy: 7-10 days; nosocomial pneumonia: 7-14 days.

Click to view RiteMED Piperacillin + Tazobactam detailed prescribing information

Overdosage

View RiteMED Piperacillin + Tazobactam overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity to penicillins, cephalosporins, β-lactamase antibiotics, or β-lactamase inhibitors.

Click to view RiteMED Piperacillin + Tazobactam detailed prescribing information

Special Precautions

Hypersensitivity. Cystic fibrosis, bowel inflammation, bleeding problems, CHF or kidney problems; patient on dialysis; history of severe diarrhea or bowel problems due to antibiotics, & if on a salt-restricted diet or have low blood K levels. Concomitant use w/ herbal prep or dietary supplement. Pregnancy & lactation.

Click to view RiteMED Piperacillin + Tazobactam detailed prescribing information

Use In Pregnancy & Lactation

Click to view RiteMED Piperacillin + Tazobactam detailed prescribing information

Adverse Reactions

Agitation; constipation; diarrhea; dizziness; headache; indigestion; nausea; pain; swelling or redness at inj site; sleeplessness; vomiting. Severe allergic reactions (rash; hives; itching; difficulty of breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; chest pain; decreased urination; depression; fainting; fast, slow or irregular heartbeat; fever; chills or sore throat; hallucination; inflammation at inj site; prolonged muscle relaxation; red, swollen or blistered skin; seizure; severe diarrhea, vomiting, or stomach pain; shortness of breath; swelling of the hands, ankles, or feet; tremor; unusual tiredness or weakness; vag irritation or discharge; vein inflammation or tenderness; yellowing of the eyes or skin.

Click to view RiteMED Piperacillin + Tazobactam detailed prescribing information

Drug Interactions

Decreased effectiveness of aminoglycosides (eg, tobramycin) or OCs; warfarin. Increased blood K levels w/ chemotherapy or diuretics (eg, furosemide, hydrochlorothiazide). Concomitant use increases side effects of heparin, MTX, or nondepolarizing muscle relaxants (eg, vecuronium). Increased risk of side effects w/ probenecid. Decreased effectiveness w/ tetracyclines (eg, doxycycline).

Click to view RiteMED Piperacillin + Tazobactam detailed prescribing information

Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view RiteMED Piperacillin + Tazobactam detailed prescribing information

Storage

View RiteMED Piperacillin + Tazobactam storage conditions for details to ensure optimal shelf-life.

Description

View RiteMED Piperacillin + Tazobactam description for details of the chemical structure and excipients (inactive components).

Action

View RiteMED Piperacillin + Tazobactam mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Penicillins

ATC Classification

J01CR05 - piperacillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

RiteMED Piperacillin +Tazobactam powd for inj

Packing/Price

10 mL x 1's (P1,046.4/vial)

RiteMED Piperacillin + Tazobactam

piperacillin + tazobactam

Manufacturer:

RiteMED

Distributor:

RiteMED