Merop Dosage & Drug Information

Indications/Uses

Treatment of susceptible infections including intra-abdominal, resp tract (including cystic fibrosis patients), skin & urinary tract; meningitis, septicemia, infections in immunocompromised patients.

Dosage/Direction for Use

IV Adult Nosocomial & ventilator-associated pneumonia, septicemia, gynecologic infections eg endometritis, skin & skin structure infections 500 mg. UTI, presumed infections in neutropenic patients 1 g. Cystic fibrosis Up to 2 g. Bacterial meningitis 2 g. Childn 4-18 yr w/ cystic fibrosis 25-40 mg/kg. Childn >3 mth-12 yr 10-20 mg/kg. Childn >50 kg Adult dosage. All doses are to be administered 8 hrly.

Contraindications

Hypersensitivity.

Special Precautions

Renal impairment (CrCl <51 mL/min). Partial cross-allergenicity w/ other carbapenems & β-lactams, penicillins & cephalosporins. Pregnancy & lactation. Infant <3 mth.

Adverse Reactions

Inflammation, thrombophlebitis, inj site pain, rash, pruritus, urticaria, abdominal pain, nausea, vomiting, diarrhea. Pseudomembranous colitis.

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Drug Interactions

Increased elimination t_½ & plasma conc w/ probenecid.

MIMS Class

Other Beta-Lactams

ATC Classification

J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.

Regulatory Classification

Rx

Presentation/Packing

Form

Merop powd for inj 1 g

Packing/Price

1's (P1,995.65/vial)

Form

Merop powd for inj 500 mg

Packing/Price

1's (P1,149.96/vial)

Merop

meropenem

Manufacturer:

UNILAB, Inc

Distributor:

UNILAB, Inc