Flumist

Prophylaxis & treatment of seasonal allergic rhinitis (including hay fever) & perennial rhinitis.

Prophylaxis & treatment of seasonal allergic rhinitis & perennial rhinitis Adult including elderly & childn >12 yr 2 sprays into each nostril once daily, preferably in the morning. In some cases, 2 sprays into each nostril bid may be required. Maintenance dose: 1 spray/nostril once daily may be used. Max daily dose: 4 sprays into each nostril. Childn 4-11 yr 1 spray into each nostril once daily preferably in the morning. In some cases, 1 spray into each nostril bid may be required. Max daily dose: 2 sprays into each nostril. Max relief may not be obtained until after 3-4 days of treatment.

Hypersensitivity.

Intranasal route only. Avoid contact w/ eyes. Local infections. Treat infections of nasal airways appropriately. Transferring patients from systemic steroid treatment to Flumist if there is any reason that adrenal function is impaired. Abnormally heavy challenge of summer allergens may necessitate appropriate additional therapy. Potential systemic effects eg, Cushing's syndrome, cushingoid features, adrenal suppression, growth retardation in childn & adolescents, range of psychological or behavioural effects including psychomotor hyperactivity, sleep disorders, anxiety, depression or aggression (particularly in childn). Regularly monitor height of childn receiving prolonged treatment w/ nasal corticosteroids. Avoid concomitant use w/ ritonavir. Increased risk of systemic side effects w/ other potent CYP3A inhibitors. Visual disturbance. Refer to an ophthalmologist for evaluation of possible causes if patient presents w/ symptoms eg, blurred vision or other visual disturbances after use of systemic & topical corticosteroids. Contains benzalkonium Cl which may cause bronchospasm; irritation or swelling inside the nose (prolonged use). Pregnancy & lactation.

Epistaxis. Headache, unpleasant taste/smell; nasal dryness/irritation, throat dryness/irritation.

Increased plasma conc resulting in markedly reduced serum cortisol conc w/ ritonavir. Increased systemic exposure (resulting in greater reduction of plasma cortisol) & risk of systemic side effects w/ ketoconazole, itraconazole; cobicistat-containing products.

Nasal Decongestants & Other Nasal Preparations

D07AC17 - fluticasone ; Belongs to the class of potent (group III) corticosteroids. Used in the treatment of dermatological diseases.
R01AD08 - fluticasone ; Belongs to the class of topical corticosteroids used for prophylaxis and treatment of allergic rhinitis.

Rx