Drofepen Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Doripenem

Indications/Uses

Nosocomial pneumonia (including ventilator-associated pneumonia), complicated intra-abdominal infection & complicated UTI including pyelonephritis.

Click to view Drofepen detailed prescribing information

Dosage/Direction for Use

Patient ≥18 yr Complicated intra-abdominal infection 500 mg 1 hr IV infusion every 8 hr for 5-14 days. Complicated UTI including pyelonephritis 500 mg 1 hr IV infusion every 8 hr for 10 days. May be extended up to 14 days for patients w/ concurrent bacteremia. Renal impairment CrCl ≥30 to ≤50 mL/min 250 mg IV (over 1 hr) every 8 hr, >10 to <30 mL/min 250 mg IV (over 1 hr) every 12 hr.

Click to view Drofepen detailed prescribing information

Overdosage

View Drofepen overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity. Anaphylactic reactions to β-lactams.

Click to view Drofepen detailed prescribing information

Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Drofepen detailed prescribing information

Special Precautions

Previous hypersensitivity reactions w/ other carbapenems, cephalosporins, penicillins or other allergens. Cross-hyperreactivity w/ β-lactams. Discontinue if C. difficile-associated diarrhea is suspected. Frequently monitor serum valproic acid conc after initiating therapy. May increase the risk of the development of drug-resistant bacteria. Moderately & severely impaired renal function. Pregnancy & lactation. Childn. Elderly.

Click to view Drofepen detailed prescribing information

Use In Pregnancy & Lactation

Click to view Drofepen detailed prescribing information

Adverse Reactions

Headache, nausea, diarrhea, rash & phlebitis.

Click to view Drofepen detailed prescribing information

Drug Interactions

May reduce serum valproic acid conc. Increased plasma conc w/ probenecid.

Click to view Drofepen detailed prescribing information

Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Drofepen detailed prescribing information

Storage

View Drofepen storage conditions for details to ensure optimal shelf-life.

Description

View Drofepen description for details of the chemical structure and excipients (inactive components).

Action

View Drofepen mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Other Beta-Lactams

ATC Classification

J01DH04 - doripenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Drofepen powd for infusion 500 mg

Packing/Price

1's

Drofepen

doripenem

Manufacturer:

BDR Pharmaceuticals

Distributor:

Ambica