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Ampicillin - Intravenous/Intramuscular


Patient Medicine Information
Why do I need this medicine?
Ampicillin is an antibiotic. It is used to treat bacterial infections of the ear, nose, throat, lungs, skin, stomach, blood stream, bladder and genitals.

This medicine may be used to treat other conditions as decided by your doctor.
How do I use this medicine?
Ampicillin injection is to be given intravenously (into the vein) or intramuscularly (into the muscle).

Your doctor or nurse will administer it for you.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your infection.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Ampicillin.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
When should I not use this medicine?
Do not use Ampicillin if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to penicillin antibiotics (e.g. amoxicillin, cloxacillin, penicillin V, sultamicillin) and cephalosporin antibiotics (e.g. cefaclor, cefalexin, cefuroxime).
What should I take note of while using this medicine?
Inform your doctor if you have the following conditions:
  • kidney disease
  • glandular fever (a type of viral infection)
  • infectious mononucleosis (a viral infection also known as “mono” or “kissing disease”)
  • lymphatic leukaemia (a type of cancer of the blood and bone marrow)
  • HIV infection
Let your doctor know if you are pregnant or breastfeeding.

If you are diabetic, this medicine may interfere with results of urine tests for sugars. Discuss with your doctor how you should monitor your urine tests while taking this medicine.
What side effects could I experience?
Ampicillin may cause any of the following side effects: diarrhoea, nausea and vomiting.

If you have diarrhoea, drink lots of water to replace the fluids lost. However, if you have severe diarrhoea or diarrhoea with severe stomach cramps or bloody stools, alert your doctor immediately.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • rashes, breathlessness, swelling of the face, eyes or mouth
  • peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
  • frequent and persistent sore throat with fever
  • unusual bleeding or bruising
  • seizures
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Inform your doctor and pharmacist if you are taking or using any of these medicines:
  • medicines for gout e.g. probenecid, allopurinol
  • other antibiotics e.g. tetracyclines, erythromycin, chloramphenicol
  • birth control pills
This list does not include all medicines that may interact with Ampicillin.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on Ampicillin - Intravenous/Intramuscular and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2025 MIMS. All rights reserved. Powered by MIMS.com
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