News &amp; Updates

Women who are experiencing menopausal transition are at risk of impaired sexual function, a study has found.

Original New Drug Application Approvals by US FDA (01 - 15 September 2022)

New drug applications approved by US FDA as of 01 - 15 September 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Any upside to frontline mFOLFOXIRI-panitumumab in mCRC?

In patients with unresectable RAS and BRAF wildtype metastatic colorectal cancer (mCRC), a modified FOLFOXIRI plus panitumumab (mFOLFOXIRI/PAN*) treatment strategy in the first-line setting did not improve objective response rate (ORR) compared with FOLFOX plus panitumumab (mFOLFOX6/PAN**), results of the phase III TRIPLETE study showed.

14 Sep 2022

MRNA booster shot durably bolsters defenses against severe COVID-19

Boosting with an mRNA vaccine yields significant protection against severe COVID-19 and may keep people out of the hospital for up to 6 months, as shown in a Singapore study.

14 Sep 2022

High tea intake helps prolong life

Drinking two or more cups of tea per day appears to lower the risk of mortality, regardless of genetic variation in caffeine metabolism, results of a prospective cohort study have shown.

Airway clearance, exercise common physiotherapy practice in adult ICUs in Singapore

Conventional airway clearance is still the most used treatment among all the available physiotherapy management techniques for patients in the intensive care unit (ICU), according to a Singapore study.

Early rhythm control reduces CV complications in low-risk AF patients

Use of early rhythm control therapy for atrial fibrillation (AF) in preventing adverse cardiovascular (CV) outcomes also benefits patients with low stroke risk in routine clinical practice, suggests a recent study.

Phase II data reveal treatment potential of pegozafermin for severe hypertriglyceridaemia

The phase II ENTRIGUE trial presented at ESC 2022 showed the potential of pegozafermin to improve triglyceride levels and other lipid-related metrics in individuals with severe hypertriglyceridaemia.

Prescription meds tied to nutritional status in CKD

Patients with chronic kidney disease (CKD) often need to take several prescription medicines concurrently, which in turn appears to worsen nutritional status, a recent study has found.

Nicorandil improves PCI outcomes in STEMI patients