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No benefit to SGLT2 inhibitor therapy in hospitalized COVID-19 patients
Adding sodium–glucose co-transporter-2 (SGLT2) inhibitors to usual care in the treatment of hospitalized patients with COVID-19 does not necessarily lead to improved survival, according to the results of a meta-analysis.
Diabetes, insulin use up risk of death, cardiac events in AF patients
In patients with atrial fibrillation (AF), being diabetic contributes to an increased risk of all-cause death, cardiovascular disease (CVD), myocardial infarction (MI), major bleeding, and major adverse cardiovascular events (MACE), results of the GLORIA-AF study have shown.
Vitamin D deficiency tied to higher T2D risk
Increased serum concentration of 25(OH)D appears to contribute to a reduced risk of type 2 diabetes (T2D) across the glycaemic spectrum below the threshold for diabetes, reports a study. Improving the lipid profile may be partly responsible for the favourable association.
SGLT-2 inhibitors may prevent dementia in adults with T2D
Initiation of sodium-glucose cotransporter-2 (SGLT-2) inhibitors results in a 35-percent reduced risk of dementia compared with dipeptidyl peptidase-4 (DPP-4) inhibitors in individuals with type 2 diabetes (T2D) aged 40–69 years, according to a study. In addition, greater benefits are seen with longer treatment duration.