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AI predicts blood concentration of quetiapine in patients with schizophrenia, depression
A machine learning model that incorporates artificial intelligence (AI) techniques to predict the blood concentration of quetiapine is feasible for clinical medication guidance in patients with schizophrenia and depression, reports a real-world study.
Functional anorectal pain ups incidence of ED, depression, anxiety in men
Men with functional anorectal pain (FARP) are more vulnerable to erectile dysfunction (ED), depression, and anxiety, a study has shown. Moreover, the incidence of these conditions increases with pain severity.
Add-on esketamine beneficial to patients with fluctuating antidepressant response
A single dose of esketamine appears to enhance the efficacy of oral antidepressants for treating patients with major depressive disorder (MDD) who are experiencing fluctuating symptoms, as reported in a small study.
Comorbid depression and sleep behaviour disorder puts patients and relatives at risk of neurodegeneration
Comorbid major depressive disorder and rapid eye movement sleep behaviour disorder (MDD-RBD) is a common subtype of MDD. These patients and their first-degree relatives (FDRs) are at risk of neurodegeneration, researchers from the Chinese University of Hong Kong (CUHK) have reported.
Meta-analysis: ADHD may factor in involvement in intimate partner, sexual violence
Individuals with attention-deficit/hyperactivity disorder (ADHD) appear to be at increased risk of being involved in cases of violence, such as intimate partner and sexual violence, according to the results of a meta-analysis.
Memories of childhood maltreatment affect mental health more than the abuse itself
Young adults with memories of childhood maltreatment have a greater number of depressive or anxiety episodes in adulthood vs those with official court records but not memories of such maltreatment, a large longitudinal study has found.