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JAK inhibitors shown safe, effective in RA patients
A recent study has demonstrated the safety and efficacy of oral Janus kinase (JAK) inhibitors in patients with rheumatoid arthritis (RA) in the real-world setting, particularly in those who do not present with cardiovascular risk factors at baseline.

Transcranial direct current stimulation improves social functioning in autism spectrum disorder
A double-blind, sham-controlled study by researchers from the Hong Kong Polytechnic University shows that cathodal transcranial direct current stimulation (tDCS) of the left dorsolateral prefrontal cortex (dlPFC) paired with cognitive remediation is a feasible and effective treatment for improving social functioning and information processing in adolescents and young adults with autism spectrum disorder (ASD) who have average to borderline IQ.

Light therapy associated with improved sleep and psychobehavioural symptoms in Alzheimer’s disease
A meta-analysis of 15 randomized controlled trials (RCTs) finds that light therapy significantly improves sleep efficiency, alleviates depression and reduces agitation in patients with Alzheimer’s disease (AD), as well as lessens caregiver burden.

Myeloma patients may benefit from mezigdomide-dexamethasone doublet
In a study evaluating heavily pretreated patients with relapsed and refractory multiple myeloma (R/R MM), the combination of mezigdomide and dexamethasone showed promising preliminary efficacy, with myelosuppression and infection as primary toxicities.




