News & Updates

In patients with advanced chronic liver disease (ACLD), ratio of procoagulant factor VIII to anticoagulant protein C (FVIII/PC) is significantly prognostic of decompensation, death, and acute-on-chronic liver failure (ACLF), a new study has found. However, FVIII/PC is not related to thrombosis and does not reflect coagulation.

Refractory ascites is a severe complication of liver cirrhosis leading to poor prognosis and is curable only through liver transplantation, reports a recent meta-analysis.

Among patients with nonalcoholic fatty liver disease (NAFLD), the more severe the liver fibrosis, the higher the risk of developing extrahepatic events, a study has found. Specifically, the risk is low among patients with mild fibrosis, low but clinically relevant among those with moderate fibrosis, and high among those with severe to advanced fibrosis.

The visceral fat area (VFA) index and visceral fat density (VFD) are independently related to the prevalence of nonalcoholic fatty liver disease (NAFLD), according to a study. However, the VFD appears to have a stronger link to the incidence of NAFLD than the VFA index.

While older recipients of living donor liver transplantation (LDLT) appear to suffer from worse mortality outcomes, such deficiency may be attributable to clinical confounders, a recent study has found. In controlled analysis, older and younger patients show comparable long-term survival following LDLT.

A delayed dose reduction of tacrolimus, along with induction of basiliximab, helps suppress kidney injury in liver transplant recipients, as opposed to standard-dose tacrolimus, a recent study has found. Such benefits come with no excess risk of rejection, graft loss, or death.