News & Updates

Performing transperineal biopsy without antibiotic prophylaxis appears to be a safe procedure, with a study reporting no sepsis cases occurring among men who underwent the antibiotic-free procedure.

In a newborn-screened cohort of children with cystic fibrosis (CF), azithromycin treatment from infancy to 36 months did not reduce the extent of structural lung disease (SLD). However, it did decrease airway inflammation and morbidity and improved some clinical outcomes associated with CF lung disease, the phase III COMBAT CF study has shown.

A 12-week course of daily oral contraception with ulipristal acetate does not appear to be reliable, with a recent study showing that women who have received daily oral ulipristal acetate have progesterone concentrations that indicate ovulation during treatment.

The association between proton pump inhibitor (PPI) use and increased cardiovascular disease risk, as seen in many observational studies, is probably caused by residual confounding related to conditions with PPI treatment instead of a true correlation, as suggested by negative findings in a self-controlled case series (SCCS) study.