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Elevated homocysteine level tied to higher NAFLD risk

14 Jan 2023

Circulating homocysteine and folate concentrations appear to play a significant role in the development of nonalcoholic fatty liver disease (NAFLD), a study has shown.

14 Jan 2023

NAFLD screening a cost-effective approach among T2DM patients in SG

12 Jan 2023 by

Nonalcoholic fatty liver disease (NAFLD) screening strategies, particularly vibration-controlled transient elastography (VCTE) and fibrosis-4 (FIB-4), are a cost-effective approach to reduce disease burden among type 2 diabetes mellitus (T2DM) patients in Singapore, according to a study.

12 Jan 2023

Corticosteroid poses no excess mortality risk in drug-induced liver injury

09 Jan 2023

Treatment with corticosteroid in patients with drug-induced liver injury (DILI) does not appear to contribute to increased risk of death but rather helps normalize liver enzymes, as shown in a study.

09 Jan 2023

Albumin confers survival benefit in select patients with cirrhosis

31 Dec 2022

Treatment with albumin appears to cut the risk of death in cirrhotic patients with spontaneous bacterial peritonitis or hepatic encephalopathy, with long-term treatment potentially lowering the risk of cirrhosis complications and need for paracentesis, according to the results of a meta-analysis.

31 Dec 2022

TACE + apatinib: A potential new strategy for intermediate/advanced HCC?

28 Dec 2022 by

In patients with intermediate or advanced hepatocellular carcinoma (HCC), combining transarterial chemoembolization (TACE) with apatinib led to improvement in progression-free survival (PFS), according to a recent study from China.

28 Dec 2022

Bepirovirsen shows promise in controlling chronic HBV infection

19 Dec 2022 by

Weekly bepirovirsen treatment may help reduce HBsAg* and hepatitis B virus (HBV) DNA levels in patients with chronic HBV infection, the phase IIb B-Clear study showed.

19 Dec 2022

Depression spikes after liver cirrhosis diagnosis

17 Dec 2022

Patients who have recently been diagnosed with liver cirrhosis see a sharp increase in the risk of developing depression, a recent study has found.

17 Dec 2022

ALXN1840 generates rapid, sustained copper mobilization in Wilson disease

15 Dec 2022 by

In individuals with Wilson disease (WD), a rare disease of copper metabolism, ALXN1840 led to significantly greater copper mobilization compared with standard of care (SoC), findings from a rater-blinded phase III study have shown.

15 Dec 2022

Maralixibat improves pruritus across all PFIC types

14 Dec 2022 by

Treatment with maralixibat significantly reduced the severity of pruritus in children with progressive familial intrahepatic cholestasis (PFIC) in the MARCH-PFIC* study presented at The Liver Meeting 2022.

14 Dec 2022

Digital pathology with AI offers new insights into fibrosis regression in NASH

13 Dec 2022 by

Second harmonic generation/two-photon excitation fluorescence (SHG/TPEF) microscopy with artificial intelligence (AI) analyses reveals novel facets of treatment-induced fibrosis regression in nonalcoholic steatohepatitis (NASH), which are not normally captured by existing staging systems, reports a study.

13 Dec 2022