News & Updates

Use of aspirin after curative-intent treatment of colorectal cancer (CRC) liver metastases does not appear to improve disease-free survival and is even associated with reduced overall survival and more serious adverse events (AEs), according to the phase III ASAC trial

Individuals with hypertensive disorders of pregnancy (HDP) may be at increased risk of dementia, as suggested in a retrospective cohort study.

Use of statins is associated with a lower incidence of remote seizures following a first status epilepticus event, according to a retrospective study.

Selection of direct-oral anticoagulants (DOACs) and risk stratification can be improved when clinicians assess both polypharmacy and potential drug interactions, especially with concomitant cardiovascular drugs and site-specific bleeding risk, suggests a study.

In patients with decompensated cirrhosis and sarcopenia, dietitian-supervised intensive nutritional therapy yielded greater improvements in skeletal muscle mass, strength, and physical performance compared with routine physician-led guideline-based dietary advice, as shown in a study.

A polypill containing valsartan, amlodipine, and chlorthalidone (KDF1901) works better than the valsartan–amlodipine combination for improving blood pressure (BP) control in Asians with essential hypertension, according to a phase III study from South Korea.

Congenital toxoplasmosis, syphilis, rubella, cytomegalovirus, or herpes simplex (TORCH) infections are rare but are associated with intellectual disability and autism, as shown in a study.

Regular consumption of fast foods, confectionery, fried potatoes, sauces, sugar-sweetened beverages, and refined grains appears to increase the risks of depression and anxiety in adults, suggests a study.