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ICLAD predicts poor vascular outcomes after ischaemic stroke
The presence of intracranial large artery disease (ICLAD) is associated with poor composite vascular outcomes, myocardial infarction (MI), and vascular death, but not recurrence, in patients with acute ischaemic stroke, suggests a Singapore study.

Mavacamten reduces blood flow obstruction in adolescents with HCM
Treatment with mavacamten, compared with placebo, results in significantly greater reduction in left ventricular outflow tract (LVOT) obstruction over 28 weeks among adolescent patients with obstructive hypertrophic cardiomyopathy (HCM), as shown in the SCOUT-HCM trial.

More aggressive LDL-C reduction improves cardiac outcomes in ASCVD patients
An intensive targeting of low-density lipoprotein cholesterol (LDL-C) level (<55 mg/dL) reduces the risk of cardiovascular events at 3 years in patients with atherosclerotic cardiovascular disease (ASCVD) when compared with conventional targeting (<70 mg/dL), results of the Ez-PAVE trial have shown.





